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Emollients and photo(chemo)therapy: a call for caution
Summary
Emollients can interfere with UV light transmission during phototherapy and photochemotherapy. This interaction may significantly alter treatment outcomes, necessitating careful consideration of product use.
Area of Science:
- Dermatology
- Photobiology
- Cosmetic Science
Background:
- Emollients are widely used for skin care and medical treatments.
- Their application before UV-based therapies like phototherapy may impact treatment efficacy.
- Understanding these interactions is crucial for optimizing therapeutic outcomes.
Purpose of the Study:
- To investigate and quantify the effects of common emollients on ultraviolet (UV) light transmission.
- To determine the potential for emollients to interfere with phototherapy and photochemotherapy.
Main Methods:
- An in vitro methodology was employed, mirroring established techniques for sunscreen testing.
- UV light transmission through various emollient preparations was measured.
Main Results:
- Two tested emollients demonstrated significant photoprotective properties, capable of altering therapy.
- Oils were found to substantially increase UV light transmission.
Conclusions:
- Emollients can significantly interfere with UV light transmission during phototherapy and photochemotherapy.
- The use of emollients may substantially modify the course and effectiveness of these treatments.