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A case of acrogeria associated with late-onset focal dermal elastosis
S Tajima1, T Inazumi, T Kobayashi
1Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
Abstract:
We report a case of acrogeria. Biochemical analysis of patient fibroblasts demonstrated unaltered type III collagen synthesis. An RNA hybridization assay demonstrated that the levels of type I and elastin mRNAs were normal. The patient had multiple yellow papules on the neck, axilla and inguinal area which clinically and histologically resembled late-onset focal dermal elastosis. Both diseases may have some similar abnormal metabolism of connective tissue.