Related Experiment Videos
Systemic scleroderma and perforating granuloma annulare: differential diagnosis from calcinosis
S Tajima1, Y Suzuki, T Inazumi
1Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
Dermatology (Basel, Switzerland)
|January 1, 1996
Abstract
Background:
Systemic scleroderma is a disorder of unknown etiology with skin sclerosis. Its major histological features are swollen and homogenized collagen bundles.
Objective And Methods:
We describe 2 patients with systemic sclerosis who have multiple umbilicated nodules indistinguishable from calcinosis cutis.
Results:
Histological examinations including Von Kossa staining revealed features of perforating granuloma annulare, but not of calcinosis cutis.
Conclusion:
The association may not be fortuitous but both diseases may be etiologically related.