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Nodular balloon cell component in a cutaneous melanoma of the superficial spreading type
P Kiene1, C Petres-Dunsche, G Funke
1Department of Dermatology, University of Kiel, Germany.
Abstract:
The rare histopathologic feature of a nodular balloon cell component in a malignant melanoma of the superficial spreading type in a 46-year-old male patient is presented. Immunohistochemical analyses proved the tumor cells to express the melanocytic markers S100 protein, NK1/C3 and HMB 45 antigens in an intense and distinct pattern. The controversial theories of the pathogenesis of balloon cell changes in melanocytic neoplasms are discussed.