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Autonomic nerve affection in leprosy

K Katoch1

  • 1Central JALMA Institute for Leprosy, Tajganj, Agra.

Indian Journal of Leprosy
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Leprosy impacts the autonomic nervous system, causing issues in skin, eyes, heart, lungs, and male reproductive organs. Early multidrug treatment is crucial for managing these widespread effects.

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Area of Science:

  • Neurology
  • Dermatology
  • Ophthalmology
  • Cardiology
  • Pulmonology
  • Urology

Background:

  • Leprosy affects multiple human body systems.
  • Autonomic nerve dysfunction is a known complication of leprosy.

Purpose of the Study:

  • To review the diverse manifestations of autonomic nervous system involvement in leprosy.
  • To highlight the need for comprehensive assessment and early treatment.

Main Methods:

  • Literature review of studies on leprosy and autonomic dysfunction.
  • Analysis of reported abnormalities in various organ systems.

Main Results:

  • Skin: Anhidrosis and impaired sweating.

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  • Eyes: Iris denervation and reduced intraocular pressure.
  • Cardiac: Documented rhythm disturbances.
  • Respiratory: Impaired breath holding and cough response, indicating vagus nerve and sympathetic plexus blockade.
  • Male Genital System: Abnormal pain sensation and diminished nocturnal penile tumescence.
  • Peripheral: Involvement of nerves innervating leg capillaries.
  • Severity correlates with disease extent and duration.

    • Conclusions:

    • Leprosy causes widespread autonomic nervous system dysfunction across multiple organ systems.
    • These findings underscore the importance of prospective studies and early multidrug therapy to manage leprosy complications.