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Related Experiment Videos

Sexual behavioral changes in Alzheimer disease

C Derouesné1, J Guigot, V Chermat

  • 1Department of Neurology, Hpital de la Salpêtrière, Paris, France.

Alzheimer Disease and Associated Disorders
|January 1, 1996
PubMed
Summary

Sexual behavior changes, including indifference and modifications, are common in Alzheimer disease (AD). These changes correlate with behavioral and mood disorders, not disease severity or depression.

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Area of Science:

  • Neuroscience
  • Gerontology
  • Psychiatry

Background:

  • Alzheimer disease (AD) significantly impacts cognitive and behavioral functions.
  • Sexual behavioral changes are frequently observed in AD patients but often underreported.
  • Understanding these changes is crucial for patient care and spousal well-being.

Purpose of the Study:

  • To assess the frequency and correlates of sexual behavioral changes in individuals with Alzheimer disease.
  • To investigate the relationship between sexual changes and clinical characteristics, disease severity, and mood disorders.
  • To evaluate the impact of sexual changes on the couple's adjustment.

Main Methods:

  • Two studies were conducted involving patients diagnosed with probable or possible AD.

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  • Study 1: Medical record review of 135 patients and spouse questionnaires on sexual activity.
  • Study 2: Mail survey to spouses of 100 patients assessing sexual changes and relationship impact.

    • Main Results:

    • 50% of spouses reported sexual behavioral modifications, and 70% noted indifference to sexual activity.
    • Sexual changes correlated with behavioral and mood disorders, particularly reduced activity and emotional deficits.
    • No correlation was found between sexual changes and cognitive deficits, age, gender, or disease severity.

    Conclusions:

    • Sexual behavioral changes are prevalent in Alzheimer disease and linked to behavioral and mood disturbances.
    • These changes can be a significant source of maladjustment for couples affected by AD.
    • Further research is needed to develop interventions addressing sexual changes in AD.