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Fixed exanthema due to paracetamol
M Gómez Martínez1, C Fernández de Miguel, A Domínguez Lázaro
1Allergy Service, Clínica Puerta de Hierro, Madrid, Spain.
Summary
Fixed exanthema, a drug reaction, commonly affects skin and mucous membranes. This case highlights paracetamol as a potential cause in a 36-year-old man.
Area of Science:
- Dermatology
- Pharmacology
- Clinical Medicine
Background:
- Fixed exanthema constitutes 10% of adverse drug reactions.
- Drug-induced causes account for up to 80% of fixed exanthema cases.
Observation:
- Lesions typically manifest on genitals, perianal region, limbs, and oral mucosa.
- A 36-year-old male patient presented with fixed exanthema.
Findings:
- The patient developed fixed exanthema subsequent to paracetamol administration.
- Paracetamol is identified as the causative agent in this specific case.
Implications:
- This case underscores the importance of considering paracetamol in the differential diagnosis of fixed exanthema.
- Awareness of paracetamol-induced fixed exanthema is crucial for clinicians managing adverse drug reactions.