Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sunburn, sunscreen, and melanoma

C Donawho1, P Wolf

  • 1University of Texas M.D. Anderson Cancer Center, Department of Immunology, Houston 77030, USA.

Current Opinion in Oncology
|March 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A MR imaging procedure to measure tarsal bone rotations.

Journal of biomechanical engineering·2007
Same author

Spontaneously occurring alimentary osteofluorosis associated with proliferative gastroduodenopathy in rabbits.

Veterinary pathology·2007
Same author

Reliability of tarsal bone segmentation and its contribution to MR kinematic analysis methods.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society·2007
Same author

Foot kinematics during walking measured using bone and surface mounted markers.

Journal of biomechanics·2007
Same author

A bispecific diabody directed against prostate-specific membrane antigen and CD3 induces T-cell mediated lysis of prostate cancer cells.

Cancer immunology, immunotherapy : CII·2007
Same author

Basic data on food intake, nutrient digestibility and energy requirements of lorikeets.

Journal of animal physiology and animal nutrition·2007

Sunburns may increase melanoma risk, but more research is needed on effective sun protection. A safe sun strategy, including sunscreen and reduced exposure, is recommended.

Area of Science:

  • Dermatology
  • Oncology
  • Photobiology

Background:

  • Growing evidence links sunlight exposure, especially ultraviolet (UV) radiation, to cutaneous malignant melanoma.
  • The precise role of UV wavelengths and sunlight in melanoma development remains unclear.
  • Current data is insufficient to definitively establish the effectiveness of sunscreens in melanoma prevention.

Purpose of the Study:

  • To review epidemiologic and experimental evidence on sunburns and cutaneous malignant melanoma.
  • To assess the potential effectiveness of sunscreens in preventing melanoma.
  • To highlight the need for further research into sunlight's role in melanoma pathogenesis.

Main Methods:

  • Review of existing epidemiologic studies.
  • Analysis of experimental evidence regarding UV radiation and melanoma.

Related Experiment Videos

  • Discussion of limitations in current data and future research directions.

    • Main Results:

    • Agreement exists that sunlight contributes to melanoma etiology.
    • Specific effective UV wavebands and sunscreen efficacy for melanoma prevention are not yet defined.
    • New experimental animal models are emerging to study melanoma initiation and promotion by UV radiation.

    Conclusions:

    • The exact role of sunlight in melanoma pathogenesis requires further elucidation.
    • While definitive data is pending, a comprehensive "safe sun strategy" is advisable.
    • This strategy should integrate sunscreen use with broader measures to reduce overall sun exposure.