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Related Experiment Videos

Testing for undesirable traits in cattle: an Australian perspective

P J Healy1

  • 1Elizabeth Macarthur Agricultural Institute, Camden, New South Wales, Australia.

Journal of Animal Science
|April 1, 1996
PubMed
Summary

Autosomal recessive defects in cattle can be controlled through biochemical testing and industry programs. Crossbreeding in beef cattle and careful selection in dairy breeds are key to reducing their prevalence.

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Area of Science:

  • Veterinary Genetics
  • Animal Breeding
  • Biochemical Genetics

Background:

  • Autosomal recessive defects are a significant concern in Australian cattle populations, often leading to lethal outcomes in newborns.
  • The dissemination of these genetic defects is often linked to selective breeding for desirable traits.

Purpose of the Study:

  • To highlight the importance of defining genetic defects at a molecular level for effective disease control.
  • To discuss the success of industry-sponsored programs in reducing specific inherited disorders in cattle.

Main Methods:

  • Biochemical or molecular definition of genetic defects.
  • Development and implementation of heterozygote detection tests.
  • Industry-sponsored disease control programs targeting specific breeds and defects.

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Main Results:

  • Successful reduction in the prevalence of alpha-mannosidosis (Angus, Murray Greys), generalized glycogenosis (Brahman, Shorthorn), and citrullinemia (Holstein/Friesian).
  • Demonstrated the effectiveness of targeted genetic disease control programs.

Conclusions:

  • Defining defects biochemically enables the development of crucial heterozygote detection tests for disease management.
  • Long-term strategies include increasing crossbreeding in beef production and cautious selection in dairy industries to mitigate recessive defects.