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Intellectual output of children with chronic renal failure on continuous ambulatory peritoneal dialysis

R M Jaramillo-Solorio1, L Menodoza-Guevara, E Garcia-Lopez

  • 1Department of Pediatric Nephrology, Hospital de Pediatria, Centro Medico Nacional Siglo XXI, Mexico City, Mexico.

Insights

Pediatric patients on continuous ambulatory peritoneal dialysis (CAPD) generally maintain average intelligence quotients, despite some challenges with performance-based tasks. Child plasticity aids in coping with uremia and neurological alterations.

Area of Science:

  • Pediatric Nephrology
  • Neuropsychology
  • Child Development

Background:

  • Continuous ambulatory peritoneal dialysis (CAPD) is a treatment for pediatric kidney failure.
  • Understanding the cognitive impact of chronic illness in children is crucial for holistic care.

Purpose of the Study:

  • To quantify intelligence quotient (IQ) in children undergoing CAPD.
  • To assess cognitive function and identify potential neurological damage in this population.

Main Methods:

  • Utilized the Wechsler test to evaluate global IQ in 30 children (ages 8-18).
  • Administered the Bender test to screen for brain damage.
  • Analyzed verbal and performance IQ scores, considering factors like illness chronicity and blood urea nitrogen levels.

Main Results:

  • Most children (76.7%) exhibited average IQ; some fell into dull normal, mild retardation, or borderline categories.
  • Bender test results did not correlate with brain damage.
  • While verbal IQ was high, 34% of children scored low on performance IQ, suggesting difficulties with specific cognitive tasks.

Conclusions:

  • Childhood plasticity is a key factor in adapting to uremia and its associated neurological alterations.
  • Cognitive capacity, or IQ, reflects a child's ability to utilize resources to manage their environment.
  • Even with neurological changes, plasticity helps children maintain good global IQ during CAPD treatment, prior to transplantation.

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