Vitreous chamber elongation is responsible for myopia development in a young adult

In this case report, we present 3 years of longitudinal, refractive component data for a young adult who became myopic and progressed in myopia (late-onset myopia, LOM) during that period. We found a high correlation between refractive error and axial length (AL). The axial elongation was a consequence of the change in the vitreous chamber depth (VCD). Furthermore, the change in AL and VCD corresponded quantitatively to the change in refractive error. Corneal curvature change was not correlated with refractive error change. These findings support the suggestion that VCD is the refractive component that changes in LOM development.