Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recent developments in anxiety, stress, and depression

S E File1

  • 1Psychopharmacology Research unit, UMDS Division of Pharmacology, Guy's Hospital, London, UK.

Pharmacology, Biochemistry, and Behavior
|May 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Flumazenil-precipitated panic and dysphoria in patients dependent on benzodiazepines: a possible aid to abstinence.

Journal of psychopharmacology (Oxford, England)·2012
Same author

Flumazenil-precipitated panic and dysphoria in patients dependent on benzodiazepines: a possible aid to abstinence--authors' response.

Journal of psychopharmacology (Oxford, England)·2012
Same author

Alcohol consumption and lifestyle in medical students.

Journal of psychopharmacology (Oxford, England)·2012
Same author

Pharmacology of human memory and cognition: illustrations from the effects of benzodiazepines and cholinergic drugs.

Journal of psychopharmacology (Oxford, England)·2012
Same author

Is lorazepam-induced amnesia specific to the type of memory or to the task used to assess it?

Journal of psychopharmacology (Oxford, England)·2012
Same author

Midazolam-induced retrieval impairments revealed by the use of flumazenil: a study in surgical dental patients.

Journal of psychopharmacology (Oxford, England)·2012
Same journal

Chronic psilocin microdosing produces limited behavioral effects and does not enhance neurogenesis in rats.

Pharmacology, biochemistry, and behavior·2026
Same journal

Modulation of prefrontal NMDA receptors reveals pharmacogenetic differences between SHR and SLA16 rat strains.

Pharmacology, biochemistry, and behavior·2026
Same journal

Spontaneous oxycodone withdrawal alters behavior and oligodendrocyte-related gene expression in mice.

Pharmacology, biochemistry, and behavior·2026
Same journal

Improvement in depressive symptoms in people undergoing cognitive behavioral therapy who supplemented with probiotics: An open-label, pilot study.

Pharmacology, biochemistry, and behavior·2026
Same journal

Long-term follow-up of children with autism spectrum disorder and severe treatment-resistant behavioral symptoms treated with purified cannabidiol.

Pharmacology, biochemistry, and behavior·2026
Same journal

Fluoxetine reduces anxiety-like behavior but increases motor impairments in the early stages of a progressive model of Parkinson's disease.

Pharmacology, biochemistry, and behavior·2026
See all related articles

This review covers animal models for anxiety, exploring predator odor responses, learning effects in mazes, and neurotransmitter systems. It also examines genetic factors, 5-HT1A receptors, and stress impacts on physiological systems relevant to anxiety and depression.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Animal Behavior

Background:

  • State and trait anxiety research involves diverse animal models.
  • Understanding anxiety requires examining neurochemical and genetic underpinnings.
  • Stress impacts on physiological systems are crucial for pathological states.

Purpose of the Study:

  • To review recent advancements in animal testing for state and trait anxiety.
  • To discuss the roles of specific neurochemical systems and receptors in anxiety.
  • To explore the influence of stress on interconnected biological systems.

Main Methods:

  • Analysis of animal behavioral responses to stimuli like predator odors.
  • Investigation of learning modifications in anxiety-related tasks (e.g., plus-maze).

Related Experiment Videos

  • Examination of neurochemical systems (cholinergic, NMDA, dopaminergic, 5-HT1A) and their functions.

    • Main Results:

    • Animal models effectively measure state anxiety, influenced by learning and genetics.
    • Specific neurotransmitter systems and 5-HT1A receptors are implicated in anxiety and related behaviors.
    • Stress profoundly affects neurotransmitter, endocrine, and immune systems, contributing to anxiety and depression.

    Conclusions:

    • Animal models are valuable tools for studying anxiety and its underlying mechanisms.
    • Neurotransmitter systems and stress responses are key targets for understanding and treating anxiety disorders.
    • Further research into genetic and developmental factors can refine anxiety assessment.