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Updated: Oct 9, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
Genetic algorithms for protein structure prediction
1University of Maryland Biotechnology Institute, Rockville, MD 20850, USA.
Abstract:
Genetic algorithms are a general class of search methods that mimic natural gene-based optimization mechanisms. Mutation, cross-over and replication operations are performed on strings. When applied to structure prediction, each string describes a particular conformation of a protein molecule. There are many ways in which such search methods may be implemented. Recent results show potential for helping with protein structure prediction, but more data are needed before a complete assessment can be made.
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