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A benzoic acid glycoside from Geniostoma antherotrichum
M A Rashid1, K R Gustafson, J H Cardellina
1Laboratory of Drug Discovery Research and Development, National Cancer Institute, Frederick, MD 21702-1201, USA.
Phytochemistry
|March 1, 1996
Abstract:
Fractionation of an HIV-inhibitory organic extract of Geniostoma antherotrichum afforded a glycoside derivative, which has been characterized as 2-hydroxy-3-O-beta-D-glucopyranosyl-benzoic acid (1) on the basis of spectral analyses. The HIV-inhibitory activity of the extract was traced to polymeric tannins, while 1 was found to be inactive in the National Cancer Institute's primary anti-HIV screen.