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[Ethanol and the gastrointestinal tract]
M Mincis1, J M Chebli, S T Khouri
1Disciplina de Gastroenterologia da Escola Paulista de Medicina (EPM), São Paulo.
Arquivos De Gastroenterologia
|July 1, 1995
Summary
Ethanol consumption significantly increases the risk of cancers in the mouth, pharynx, esophagus, and colon. Alcohol abuse also contributes to gastroesophageal reflux disease, Mallory-Weiss syndrome, and impacts nutrient absorption in the small bowel.
Area of Science:
- Gastroenterology
- Oncology
- Toxicology
Context:
- Ethanol, a primary component of alcoholic beverages, exerts diverse effects on the entire gastrointestinal (GI) tract.
- Alcohol consumption is a global health concern with known associations with various diseases.
Purpose:
- To comprehensively review the multifaceted effects of ethanol on the human gastrointestinal system.
- To synthesize current research on alcohol's impact on GI health and disease incidence.
Summary:
- Ethanol increases the risk of cancers in the mouth, pharynx, esophagus, and colon.
- Alcohol consumption is linked to gastroesophageal reflux disease, Mallory-Weiss syndrome, and esophageal varices.
- Ethanol affects gastric secretion, motility, and permeability, potentially influencing acute gastritis and nutrient absorption in the small bowel.
Impact:
- Highlights the significant carcinogenic potential of ethanol across multiple GI segments.
- Underscores the role of alcohol in upper GI conditions like reflux and bleeding disorders.
- Emphasizes the need for awareness regarding alcohol's broad impact on digestive health and disease prevention.