Ocular outcome in children born before 32 weeks gestation

P M Pennefather1, M P Clarke, N P Strong

  • 1Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

Eye (London, England)
|January 1, 1995
PubMed

Insights

Premature infants born before 32 weeks gestation often experience visual impairments. Early follow-up care for these children is crucial for identifying and treating vision abnormalities like strabismus and retinopathy of prematurity.

Area of Science:

  • Ophthalmology
  • Neonatology
  • Pediatrics

Background:

  • Infants born prematurely, especially before 32 weeks gestation, are at increased risk for ocular complications.
  • Understanding the long-term visual outcomes in this vulnerable population is essential for timely intervention.

Purpose of the Study:

  • To assess the ocular outcomes at approximately 2 years of age in a cohort of children born before 32 weeks gestation.
  • To determine the incidence of specific visual abnormalities in this high-risk group.

Main Methods:

  • A 2-year cohort study was conducted within a defined population of 3 million.
  • 565 children born before 32 weeks gestation were identified, and 558 (98.8%) were assessed at approximately 2 years old.

Main Results:

  • A high incidence of ocular abnormalities was observed, including strabismus (12.5%), significant refractive errors (12.7%), sequelae of retinopathy of prematurity (2.9%), and cortical visual loss (1.3%).
  • These findings highlight the significant visual morbidity in this cohort.

Conclusions:

  • The study provides recent, gestational age-specific prognostic data for premature infants.
  • Regular ophthalmological follow-up for preterm infants is critical for detecting visual impairments that can benefit from treatment.

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...