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Skull osteomyelitis due to Salmonella species: two case reports and review
A Kamarulzaman1, R J Briggs, G Fabinyi
1Department of Neurosurgery, Austin Hospital, Melbourne, Victoria, Australia.
Abstract:
Osteomyelitis of the skull is a rare disease. We describe two cases due to Salmonella typhimurium and review 10 previously reported cases of salmonella osteomyelitis of the skull. This infection is frequently complicated by extradural abscess, which may be asymptomatic. Diagnostic imaging by means of computed tomographic scanning with contrast or gadolinium-enhanced magnetic resonance imaging should be performed to detect this complication. A good outcome can be expected with a combination of surgery and antibiotic therapy.
Insights
Skull osteomyelitis caused by Salmonella typhimurium is rare but can lead to asymptomatic extradural abscesses. Early diagnosis with advanced imaging and prompt treatment combining surgery and antibiotics improve patient outcomes.
Area of Science:
- Infectious Diseases
- Neurosurgery
- Radiology
Background:
- Osteomyelitis of the skull is an uncommon condition.
- Salmonella typhimurium is a rare causative agent of skull osteomyelitis.
- Extradural abscesses are frequent, often asymptomatic, complications.