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Related Experiment Videos

Relapsing polychondritis presented as inner ear involvement

Y Kimura1, H Miwa, M Furukawa

  • 1Department of Otolaryngology, Kanazawa University School of Medicine, Japan.

The Journal of Laryngology and Otology
|February 1, 1996
PubMed
Summary
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This case study highlights relapsing polychondritis presenting with inner ear symptoms. Early steroid treatment was effective, with Chinese herbal medicine successfully managing relapsing polychondritis.

Area of Science:

  • Rheumatology
  • Otolaryngology
  • Internal Medicine

Background:

  • Relapsing polychondritis is a rare multisystem inflammatory disease.
  • Auricular chondritis is the most common initial symptom, but not always present.
  • Diagnosis can be challenging with atypical presentations.

Observation:

  • A 53-year-old Japanese man presented with sudden hearing loss, tinnitus, and dizziness.
  • Initial symptoms lacked auricular chondritis, delaying diagnosis.
  • Steroid therapy (prednisolone) was initiated and showed initial efficacy.

Findings:

  • Prednisolone dose reduction led to increased C-reactive protein levels.
  • Low-dose methotrexate was discontinued due to severe gastrointestinal side effects.

Related Experiment Videos

  • Adjunctive therapy with Sho-saiko-to (a Chinese herbal medicine) resulted in marked improvement.

    • Implications:

    • Inner ear involvement can be the initial presentation of relapsing polychondritis.
    • Atypical presentations require careful diagnostic consideration.
    • Chinese herbal medicine may offer a safe and effective adjunctive treatment option for relapsing polychondritis.