Related Experiment Videos
Direct chiral resolution of 15-deoxyspergualin using a cellobiohydrolase liquid chromatographic column
D J Mayo1, F P Tomasella, J E Noroski
1Bristol-Myers Squibb Pharmaceutical Research Institute, New Brunswick, NJ 08903-0191, USA.
Journal of Pharmaceutical and Biomedical Analysis
|February 1, 1996
Abstract:
An LC method for the direct determination of the enantiomers of 15-deoxyspergualin was developed, optimized and validated. A commercially available LC column containing a cellulase enzyme (cellobiohydrolase I) stationary phase was used. The effect of various parameters on the separation and validation data are discussed.