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Characterization of cryoglobulins: some remarks on methodology
D Campioli1, M Ghini, M T Mascia
1Dipartimento Medicina Interna, Cattedra di Reumatologia, Università di Modena, Italy.
Clinical and Experimental Rheumatology
|November 1, 1995
Abstract
Objective:
The experience of our group in the characterization of the cryoglobulins during the last 8 years is reported, and the possible advantages of immunofixation versus immunoblotting are discussed.
Methods:
25 out of 171 cryoprecipitates studied by immunofixation were also examined by immunoblotting, a technique which has been suggested to offer advantages in analysing monoclonal components.
Results:
We confirm that immunofixation may be the technique of choice given its easier execution and interpretation, better standardization, and lower overall cost.