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Anti-GOR antibodies, HCV, liver disease and cryoglobulinemia
F Saccardo1, G Monti, G Rinaldi
1Ia Division of Medicine, Saronno Hospital, Italy.
Objective:
We investigated the presence of anti-GOR antibodies in patients with essential mixed cryoglobulinemia, since both autoimmune pathogenetic processes and a high prevalence of HCV infection are present in this syndrome.
Methods:
We compared these cases to patients with HCV-related chronic active hepatitis or alcoholism, and to ex-blood donors. A total of 60 patients with biopsy-proven chronic liver disease were studied.
Results:
HCV related markers, cryoglobulins, anti-GOR antibodies and ANA were detected in all of the groups.
Conclusion:
Our data would appear to indicate that anti-GOR are related to the presence of HCV chronic hepatitis and not to cryoglobulinemia or chronic liver damage.