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Related Experiment Videos

Total radical trapping antioxidant potential (TRAP) and exercise

P C Sharpe1, E B Duly, D MacAuley

  • 1Department of Clinical Biochemistry, Ulster Hospital, Dundonald, UK.

QJM : Monthly Journal of the Association of Physicians
|March 1, 1996
PubMed
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Physical activity and fitness did not directly increase antioxidant levels (total radical trapping antioxidant potential - TRAP). This population study found TRAP was lower in smokers and varied by sex, age, and BMI, but not fitness.

Area of Science:

  • Human Health and Nutrition
  • Biochemistry and Oxidative Stress

Background:

  • Antioxidant status is crucial for mitigating oxidative stress.
  • Physical activity is generally associated with improved health markers.
  • The direct link between physical activity, fitness, and antioxidant capacity requires further population-based investigation.

Purpose of the Study:

  • To investigate the relationship between physical activity, physical fitness, and total radical trapping antioxidant potential (TRAP).
  • To examine demographic and lifestyle factors influencing antioxidant status in a general population sample.

Main Methods:

  • Cross-sectional population study (n=1600) using a two-stage probability sample.
  • TRAP calculated from serum concentrations of urate, protein thiols, ascorbate, alpha tocopherol, and bilirubin.

Related Experiment Videos

  • Physical fitness estimated via VO2max extrapolation; physical activity assessed by computer-assisted interview.

    • Main Results:

    • Mean serum TRAP was significantly higher in males than females (p < 0.0001).
    • Smokers exhibited significantly lower TRAP values compared to non-smokers (p < 0.0001 for males, p = 0.02 for females).
    • In females, TRAP showed positive associations with age and BMI, but a negative association with physical fitness (p < 0.05).

    Conclusions:

    • Physical activity and fitness do not appear to directly enhance antioxidant status.
    • Factors such as smoking, sex, age, and BMI significantly influence antioxidant potential.
    • The health benefits of exercise may be mediated through pathways other than direct increases in antioxidant capacity.