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[Prevalence of diabetic nephropathy in adult patients with chronic kidney failure]
J B Lopes de Faria1, Z Z Bittencourt, M A Ribeiro Alves
1Departamento de Clínica Médica da Faculdade de Ciências Médicas da UNICAMP, Campinas.
Unlabelled:
Diabetic nephropathy is a frequent cause of end-stage renal failure in patients admitted for renal replacement therapy.
Purpose:
To evaluate the prevalence of DN, as the underline disease, in patients with ESRF.
Methods:
1,303 [male (M) = 767 and female (F) = 536] patients with ESRF who were on a waiting list for cadaver kidney transplant at Nephrology Unit-University Hospital (HC-UNICAMP), from August/90 to June/93--group 1--and 193 (M = 112 and F = 81) patients admitted for renal replacement therapy in a year period (April/92 to March/93), in the city of Campinas, State of São Paulo, Brazil, were studied.
Results:
The prevalence of DN was 10.1% in group 1 and 17.6% in group 2 (x2 = 7.15; p = 0.007), being the third cause of ESRF in both groups, and it was preceded by glomerulonephritis and arterial hypertension. In group 1 the reduction of number of patients with increase in duration of dialysis was significantly greater in patients with diabetic nephropathy (x2 = 30.9; p < 0.001). Among patients with DN 35 (26%) in group 1 and 6 (18%) in group 2 had less than 35 years when they were admitted for renal replacement therapy and are likely to be type 1 (insulin-dependent) diabetic patients.
Conclusion:
In our studied groups DN was a frequent cause of ESRF.