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[A preliminary observation on the effects of inhaled nitric oxide on bronchial asthma]
1Beijing Respiratory Disease Research Center, Beijing Red Cross ChaoYang Hospital.
Zhonghua Nei Ke Za Zhi
|December 1, 1995
Abstract:
Nitric oxide (NO) is a vasodilator as well as a bronchodilator. In order to estimate the therapeutic effects of NO on bronchial asthma, 10 patients in acute exacerbation stage were selected for this study. 40 ppm NO was inhaled for 20 minutes. The clinical stage and pulmonary function were evaluated instantly. The results showed that subjective symptoms were relieved and wheezing rales decreased to a different extent, FEV1 and PEF improved significantly (P < 0.05). It is suggested that low concentration NO inhalation can be used as a therapeutic measure for bronchial asthma.