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The retrospective study on high risk factors of subphrenic infection after hepatectomy
Abstract:
In order to identify the high risk factors that determine subphrenic infection after hepatectomy, 187 liver resections performed during January, 1985 to December, 1990 in Department of Surgery of Tongji Hospital were reviewed. Thirteen patients developed subphrenic infection with the incidence of subphrenic infection being 6.95%. The results of retrospective study on 187 liver resections demonstrated that the high risk factors related to subphrenic infection after hepatectomy were as follows: (1) The extent of liver resection was associated with subphrenic infection. (2) The incidence of subphrenic infection after liver resection of primary liver cancer patients with hepatic cirrhosis was higher than that of non-cirrhotic patients. (3) Intraoperative estimated blood loss greater than 1500 ml was found to be a significant risk factor in the development of postoperative subphrenic infection. (4) Adequate postoperative drainage of subdiaphragm and the raw surface of the liver was one of critical factors of decreasing subphrenic infection after liver resection.
Insights
Subphrenic infection after hepatectomy is linked to extensive liver resection, primary liver cancer with cirrhosis, and significant blood loss. Adequate drainage is key to prevention.
Area of Science:
- Hepatobiliary Surgery
- Surgical Infections
- Oncology
Background:
- Subphrenic infection is a significant postoperative complication following hepatectomy.
- Identifying high-risk factors is crucial for improving patient outcomes and surgical strategies.
Purpose of the Study:
- To identify high-risk factors associated with subphrenic infection after liver resection.
- To analyze the incidence and determinants of subphrenic infection in patients undergoing hepatectomy.
Main Methods:
- Retrospective review of 187 liver resections performed between January 1985 and December 1990.
- Analysis of patient data to correlate specific factors with the development of subphrenic infection.
Main Results:
- The overall incidence of subphrenic infection was 6.95% (13 out of 187 patients).
- High-risk factors identified include: extent of liver resection, primary liver cancer in cirrhotic patients, and intraoperative blood loss >1500 ml.
- Adequate postoperative drainage of the subdiaphragm and liver raw surface was found to decrease infection rates.
Conclusions:
- The extent of liver resection, presence of liver cirrhosis in primary liver cancer patients, and substantial intraoperative blood loss are significant risk factors for subphrenic infection post-hepatectomy.
- Effective postoperative drainage is a critical factor in reducing the incidence of subphrenic infection.
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