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In vitro cytotoxicity and immunomodulating property of Rhaphidophora korthalsii
1Department of Pharmacology, Faculty of Medicine, National University of Singapore, Singapore.
Journal of Ethnopharmacology
|May 1, 1996
Abstract:
An in vitro cytotoxic screening of extracts of Rhaphidophora korthalsii indicated cytotoxicity in the ether fraction. ED50 values of the extract against P388, Molt 4, KB and SW 620 were 12, 14, 8 and 13 micrograms/ml, respectively. The extract was relatively more toxic on P388 and Molt 4 cell lines at concentrations of 50 micrograms/ml and 100 micrograms/ml. Screening with mouse splenocytes showed that the hot water extract had splenocytes stimulating activity.