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Hydronephrosis in children after bone marrow transplantation: case reports
J Kapelushnik1, A Verstandig, R Or
1Department of Bone Marrow Transplantation, Hadassah University Hospital, Jerusalem, Israel.
Bone Marrow Transplantation
|May 1, 1996
Summary
Hydronephrosis after bone marrow transplantation (BMT) in children can stem from various causes. Importantly, this condition did not impact BMT outcomes, suggesting conservative management approaches.
Area of Science:
- Pediatric Nephrology
- Hematology
- Transplantation Medicine
Background:
- Bone marrow transplantation (BMT) is a critical treatment for various pediatric conditions.
- Hydronephrosis, a condition of urine backup and kidney swelling, can occur post-BMT.
- Understanding the causes and impact of post-BMT hydronephrosis is crucial for patient management.
Observation:
- Five pediatric cases of hydronephrosis following BMT were identified.
- Causes included hemorrhagic cystitis, bladder blood clots, ureteropelvic junction stenosis, and adenoviral ureteral obstruction.
- All patients received conservative symptomatic treatment.
Findings:
- The identified causes of hydronephrosis varied, highlighting diverse etiologies.
- Conservative management was employed for symptomatic relief.
- Crucially, the presence of hydronephrosis did not adversely affect the overall outcome of BMT.
Implications:
- The findings suggest that hydronephrosis post-BMT may not necessitate aggressive intervention.
- Less invasive treatment strategies could be considered for pediatric patients with post-BMT hydronephrosis.
- This approach may improve patient comfort and reduce treatment-related complications without compromising transplant success.