[Joint and systemic manifestations related to type 2 anti-mitochondrial antibodies]

The aim of the study was to assess the significance of type 2 anti-mitochondrial antibodies in patients with systemic and inflammatory rheumatic disease. Articular and systemic manifestations of 8 patients associated with type 2 anti-mitochondrial antibodies are described. All the patients had hepatic abnormalities, and 5 of them disclosed a primary biliary cirrhosis. Articular and systemic manifestations were similar to those observed in primary biliary cirrhosis. Therefore, the finding of anti-mitochondrial antibodies in patients with systemic or inflammatory rheumatic disease implies research for other systemic manifestations such as primary biliary cirrhosis.