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Related Experiment Videos

[Non-neoplastic hypercalcitoninemia. Pathological anatomy]

J P Saint-André1, S Guyétant

  • 1Laboratoire d'Anatomie Pathologique, CHU, Angers.

Annales D'Endocrinologie
|January 1, 1996
PubMed
Summary

C-cell hyperplasia (CCH) is common in various thyroid conditions and normal individuals. However, it is considered pre-neoplastic only in MEN2 patients with RET mutations, otherwise it is reactive or normal.

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Area of Science:

  • Endocrinology
  • Oncology
  • Pathology

Background:

  • Normal C-cells are a minor component of the thyroid gland.
  • C-cell hyperplasia (CCH) is defined by specific microscopic criteria.
  • CCH is observed in familial contexts like MEN2 and other thyroid conditions.