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Penicillin as a supplement in resolving the localized acute apical abscess
A F Fouad1, E M Rivera, R E Walton
1Department of Restorative Dentistry and Endodontology, University of Connecticut Health Center, Farmington, USA.
Summary
Penicillin supplementation did not significantly improve recovery for acute apical abscesses. Localized endodontic emergencies typically resolve quickly with appropriate local treatment and pain management.
Area of Science:
- Endodontics
- Microbiology
- Pharmacology
Background:
- Antibiotic overuse is common in endodontic emergencies.
- The efficacy of antibiotic supplementation for localized acute apical abscesses remains unclear.
Purpose of the Study:
- To evaluate the impact of penicillin supplementation on symptom reduction.
- To assess the recovery trajectory of localized acute apical abscesses following emergency treatment.
Main Methods:
- A double-blind, randomized study involving patients with pulp necrosis and localized periapical symptoms.
- Participants were assigned to penicillin VK, placebo, or no medication groups.
- Pain and swelling were monitored using a visual analog scale for 72 hours, with all patients receiving ibuprofen.
Main Results:
- Most patients experienced rapid symptom resolution.
- No statistically significant differences in recovery or symptom course were observed between the penicillin, placebo, and no medication groups (p < 0.05).
Conclusions:
- Localized periapical pain and swelling generally resolve effectively with standard local endodontic treatment.
- Penicillin supplementation did not demonstrate a significant benefit in the recovery of localized acute apical abscesses in this study.