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Related Experiment Videos

Multiple pregnancies: the price to pay

J Salat-Baroux1, J M Antoine

  • 1Department of Gynaecology, Obstetrics and Biology of Reproduction, University Paris VI, Hôpital Tenon, France.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|April 1, 1996
PubMed
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Assisted reproductive technology has increased multiple pregnancies tenfold, leading to higher rates of prematurity, mortality, and intensive care admissions. Reducing the number of embryos transferred, not selective reduction, is key to improving outcomes.

Area of Science:

  • Reproductive Medicine
  • Perinatology
  • Public Health

Background:

  • Assisted reproductive technology (ART) has dramatically increased multiple pregnancies since 1980.
  • Twin pregnancies and those from simple ovulation stimulation show the most significant rise.
  • This trend has substantial implications for maternal and infant health outcomes.

Purpose of the Study:

  • To analyze the impact of rising multiple pregnancies due to ART.
  • To quantify the associated risks and costs.
  • To evaluate potential solutions for mitigating these adverse effects.

Main Methods:

  • Analysis of epidemiological data on ART-induced pregnancies.
  • Statistical review of prematurity, perinatal mortality, and neonatal intensive care unit (NICU) admission rates.

Related Experiment Videos

  • Cost-benefit analysis of ART outcomes.

    • Main Results:

    • Multiple pregnancies have increased tenfold since 1980, primarily twin gestations.
    • ART-related multiple births show an 82% prematurity rate, a 74% increase in perinatal mortality, and 95% NICU admission.
    • Cost per child increases significantly with multiples (1.9x for twins, 3.7x for triplets).

    Conclusions:

    • Reducing the number of embryos transferred is a more effective strategy than selective embryo reduction.
    • ART protocols should prioritize single embryo transfer to minimize risks.
    • Addressing ART-induced multiple pregnancies is crucial for improving infant survival and reducing healthcare costs.