Related Experiment Video
Updated: Aug 11, 2026

Generation of an Immortalized Murine Brain Microvascular Endothelial Cell Line as an In Vitro Blood Brain Barrier Model
Published on: August 29, 2012
Endothelial cells of the brain and other organ systems: some similarities and differences
1Laboratory of Molecular Neurobiology, Institute of Biophysics, Biological Research Centre of the Hungarian Academy of Sciences, Szeged, Hungary.
Abstract:
The cerebral endothelium represents an active interface between blood and central nervous system. The blood-brain barrier restricts the free passage of nutrients, hormones, drugs and cellular elements to the brain. Recent studies performed on freshly isolated cerebral microvessels and cultured endothelial cells of brain capillaries provided a better understanding of the properties and functions of cerebral endothelial cells. This review summarizes the main findings of the in vitro approach in the blood-brain barrier research, describes the common endothelial and unique cerebral features of the brain endothelium, and provides a short overview on how these blood-brain barrier characteristics can be induced in cerebral endothelial cells by the neighbouring cells.
More Related Videos
09:03Differentiation of Human Induced Pluripotent Stem Cells to Brain Microvascular Endothelial Cell-Like Cells with a Mature Immune Phenotype
Published on: May 19, 2023
09:38Measuring Changes in Brain Endothelial Barrier Integrity with Two Impedance-based Biosensors in Response to Cancer Cells and Cytokines
Published on: September 22, 2023
Related Concept Videos
Tissues
The Blood-brain Barrier
Glial Cells
Overview of the Vascular System
Tissues
Capillaries and Their Types