Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neuronal control of development in hydra

H C Schaller1, I Hermans-Borgmeyer, S A Hoffmeister

  • 1Center for Molecular Neurobiology, University of Hamburg, Germany.

The International Journal of Developmental Biology
|February 1, 1996
PubMed
Summary

Hydra

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Skeletal deterioration in COL2A1-related spondyloepiphyseal dysplasia occurs prior to osteoarthritis.

Osteoarthritis and cartilage·2020
Same author

Analysis of morphogenetic mutants of hydra : I. TheAberrant.

Wilhelm Roux's archives of developmental biology·2017
Same author

Analysis of morphogenetic mutants of hydra : II. The non-budding mutant.

Wilhelm Roux's archives of developmental biology·2017
Same author

Analysis of morphogenetic mutants of hydra : III.Maxi andMini.

Wilhelm Roux's archives of developmental biology·2017
Same author

Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice.

Brain : a journal of neurology·2012
Same author

RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75.

British journal of pharmacology·2006

Area of Science:

  • Developmental Biology
  • Cellular Biology
  • Regenerative Medicine

Background:

  • Hydra's simple cell structure and regenerative capabilities make it ideal for studying pattern formation.
  • Nerve cells in Hydra produce signaling molecules that regulate cell differentiation.
  • Head activator, a peptide, plays a crucial role in Hydra's development and cell differentiation.

Purpose of the Study:

  • To investigate the role of head activator in Hydra's cellular processes.
  • To understand the signaling pathways involved in Hydra's differentiation.
  • To explore the conserved functions of head activator across species.

Main Methods:

  • Regeneration experiments in Hydra.
  • Transplantation and reaggregation studies.
  • Analysis of cellular differentiation pathways and signaling molecules.

Main Results:

  • Head activator stimulates cell division and differentiation of nerve and epithelial cells in Hydra.
  • The cyclic adenosine monophosphate (cAMP) pathway is involved in nerve cell differentiation.
  • Head activator's function is conserved in mammals, where it acts as a mitogen.

Conclusions:

  • Hydra's signaling system provides insights into fundamental developmental processes.
  • Head activator is a key regulator of cell differentiation and proliferation.
  • The conserved nature of head activator highlights its evolutionary importance in neural development.

Related Experiment Videos