Related Experiment Video
Updated: Aug 10, 2026

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An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants
Published on: November 3, 2019
Dithiocarbamates inhibit IL-1-induced cartilage degradation in bovine articular cartilage explants
1OsteoArthritis Sciences Inc., Cambridge, MA 02139, USA.
Abstract:
Interleukin-1-stimulated cartilage degradation in bovine articular cartilage explants is effectively inhibited by several different dithiocarbamates with IC50's in the micromolar range.

