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Possible interaction involving phenytoin, dexamethasone, and antineoplastic agents: a case report and review

W A Gattis1, D B May

  • 1Campbell University School of Pharmacy, Buies Creek, NC, USA.

The Annals of Pharmacotherapy
|May 1, 1996
PubMed
Abstract

Insights

Patients receiving chemotherapy and dexamethasone may require higher phenytoin doses due to subtherapeutic drug concentrations. This review explores potential drug interactions affecting phenytoin levels in cancer patients.

Area of Science:

  • Pharmacology
  • Oncology
  • Drug Interactions

Background:

  • Phenytoin is an anticonvulsant medication.
  • Chemotherapy and dexamethasone are commonly used in cancer treatment.
  • Subtherapeutic drug levels can impact treatment efficacy.

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