Rationale and treatment results with bioinjectables

Management of intrinsic sphincter deficiency (ISD) can be achieved by many techniques. Those patients suffering from urinary incontinence secondary to ISD have often undergone multiple prior procedures for management of incontinence; therefore, an ideal form of treatment would be one that is minimally invasive and safe without compromising efficacy. The bioinjectables have proved to be safe and effective for the management of ISD and offer a minimally invasive alternative that can be performed under local anesthesia. This form of therapy is especially advantageous for properly selected patients suffering from urinary incontinence caused by ISD. We review the properties, indications for use, and results of the bioinjectables used in the treatment of ISD.