Related Experiment Videos
Molecular cloning of a third chitinase gene (CHT1) from Candida albicans
K J McCreath1, C A Specht, Y Liu
1Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139, USA.
Yeast (Chichester, England)
|April 1, 1996
Abstract:
Here we report the complete nucleotide sequence of a third chitinase gene (CHT1) from the dimorphic human pathogen Candida albicans. The deduced amino acid (aa) sequence of Cht1 consists of 416 aa and displays 36% protein sequence similarity to chitinases Cht2 and Cht3, from C. albicans. Interestingly the domain structure of Cht1 is truncated when compared to the other chitinases of C. albicans and lacks a Ser/Thr-rich region.