Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Molecular chaperones and disease

B Henderson1, S P Nair, A R Coates

  • 1Maxillofacial Surgery Research Unit, Eastman Dental Institute for Oral Health Care Sciences, University College London, UK.

Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Source Attribution of PM<sub>2.5</sub> Health Benefits Over Northern Hemisphere Using Adjoint of Hemispheric CMAQ.

GeoHealth·2026
Same author

Idiopathic subglottic stenosis in Saskatchewan Hutterite population.

The Journal of laryngology and otology·2022
Same author

Multiscale Modeling of Background Ozone: Research Needs to Inform and Improve Air Quality Management.

EM (Pittsburgh, Pa.)·2020
Same author

Histoid Leprosy Presenting with Keloid Like Lesions.

Indian journal of leprosy·2018
Same author

Invited review: A position on the Global Livestock Environmental Assessment Model (GLEAM).

Animal : an international journal of animal bioscience·2017
Same author

Incident reporting, aviation and anaesthesia.

Anaesthesia and intensive care·2017
Same journal

A platelet-monocyte pyroptotic axis mediates uremic cardiomyopathy: critical role of PF4 and hematopoietic caspase-1.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2026
Same journal

Single-cell transcriptomic analysis identifies a MIF-driven keratinocyte-macrophage-Th2 axis as a key inflammatory circuit in atopic dermatitis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2026
Same journal

Agmatine induces mitophagy via the PTS-I2R pathway to increase autophagic flux and attenuate sepsis-induced intestinal epithelial cell apoptosis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2026
Same journal

Eosinophil cationic protein-driven type 2 inflammation impairs olfactory function in a murine model.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2026
Same journal

Spleen-associated macrophage alterations and embryo viability in a murine model of recurrent spontaneous abortion.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2026
Same journal

Chronic intermittent hypoxia sustains the low-grade inflammatory memory of monocytes via activation of myelopoiesis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2026
See all related articles

Molecular chaperones, vital for cell function and stress response, are increasingly recognized for their roles in tissue pathology and treatment. This review highlights their emerging importance in disease processes.

Area of Science:

  • Molecular biology
  • Cellular stress response
  • Protein folding

Background:

  • Molecular chaperones are crucial intracellular proteins involved in protein folding.
  • They are integral components of the ancient heat shock response to cellular stress.
  • Recent research highlights their essential functions in normal cell operations.

Purpose of the Study:

  • To review the established and emerging roles of molecular chaperones.
  • To explore their involvement in tissue pathology.
  • To discuss their potential in therapeutic strategies.

Main Methods:

  • Literature review of recent scientific publications.
  • Analysis of studies on molecular chaperone functions.
  • Synthesis of findings related to pathology and treatment.

Related Experiment Videos

Main Results:

  • Molecular chaperones play a vital role in maintaining cellular function.
  • Emerging evidence indicates their involvement in various tissue pathologies.
  • These proteins show potential as targets for novel therapeutic interventions.

Conclusions:

  • Molecular chaperones are critical for cellular homeostasis and stress adaptation.
  • Their dysregulation is implicated in disease pathogenesis.
  • Targeting molecular chaperones offers promising avenues for treating human diseases.