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[Urinary proteins (focusing on alkaline phosphatases)]
1Division of Clinical Chemistry, Niigata Cancer Center Hospital, Japan.
Rinsho Byori. the Japanese Journal of Clinical Pathology
|July 1, 1996
Summary
Urinary alkaline phosphatase (ALP) levels were studied before and after strenuous exercise to understand sports stress markers. Post-exercise ALP activity peaks were observed, with some originating from the kidney, suggesting a link to sports-related stress and bone health.
Area of Science:
- Sports Medicine
- Biochemistry
- Physiology
Context:
- Understanding sports-related physiological stress markers is crucial.
- Urinary alkaline phosphatase (ALP) is a potential indicator of bone metabolism.
- The effects of strenuous exercise on urinary ALP levels and patterns require further investigation.
Purpose:
- To investigate changes in urinary alkaline phosphatase (ALP) levels and isozyme patterns following strenuous exercise.
- To determine the potential origin of post-exercise urinary ALP.
Summary:
- Urinary ALP levels exhibited peak activity 5-15 minutes and 1 hour post-exercise.
- Slight increases in higher molecular mass ALP were noted after intense exercise, with no significant correlation to exercise intensity or duration.
- Analysis suggested a portion of post-exercise urinary ALP originates from the kidney, showing similar mobility to renal cortex and medulla ALP.
Impact:
- Urinary ALP is recognized as a marker for bone metabolism.
- Findings suggest urinary ALP warrants further scrutiny for its connection to sports-related stress.
- This research may contribute to understanding exercise-induced physiological changes and potential links to conditions like osteoporosis.