Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Homeostasis?01:16

What is Homeostasis?

57.4K
Maintaining homeostasis requires that the body continuously maintain its internal conditions. Each physiological condition has a particular set point, from body temperature to blood pressure to levels of certain nutrients. A set point is the physiological value around which the normal range fluctuates. A normal range is a restricted set of values that is optimally healthful and stable. For example, the set point for normal human body temperature is approximately 37°C (98.6°F).
57.4K
pH Homeostasis01:31

pH Homeostasis

20.1K
Acid-base homeostasis is essential for maintaining normal physiological activities in humans. The pH of various body fluids is strictly regulated because it is critical for the optimal activity of enzymes involved in metabolic reactions. Enzymes are basically proteins, so, any significant change in pH can affect their structure and activity. In humans, pH is regulated using three primary mechanisms— chemical buffer systems, respiratory regulation, and renal regulation.
Respiratory...
20.1K
Regulation of Sodium and Potassium01:26

Regulation of Sodium and Potassium

2.4K
The regulation of sodium and potassium ion concentrations in the human body is a complex process governed primarily by hormones such as aldosterone, antidiuretic hormone (ADH), and atrial natriuretic peptide (ANP).
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily...
2.4K
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

6.1K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
6.1K
Glucose Homeostasis: Regulation of Blood Glucose01:02

Glucose Homeostasis: Regulation of Blood Glucose

4.4K
Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
4.4K
Roles of Electrolytes: Sodium and Potassium01:24

Roles of Electrolytes: Sodium and Potassium

2.3K
Sodium plays a crucial role in maintaining fluid and electrolyte balance and overall bodily homeostasis. Sodium balance is primarily regulated by kidney function, which adjusts sodium elimination to match dietary intake and maintain proper electrolyte levels. Sodium is the most abundant cation in the extracellular fluid (ECF) and is found in salts such as sodium chloride (NaCl) and sodium bicarbonate (NaHCO3). Although cellular plasma membranes are relatively impermeable to sodium, its role in...
2.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.

Molecular and cellular biology·2000
Same author

Circadian variation in the natriuresis produced by potassium intake in the rat.

Clinical and experimental hypertension (New York, N.Y. : 1993)·1998
Same author

Early effects of uninephrectomy on K homeostasis in unanesthetized rats.

The American journal of physiology·1996
Same author

Kaliuresis in normal subjects following oral potassium citrate intake without increased plasma potassium concentration.

Nephron·1995
Same author

Circadian rhythms and time course of adaptive sodium and potassium excretion in rats after uninephrectomy.

The American journal of physiology·1994
Same author

The central nervous system in potassium homeostasis.

Frontiers in neuroendocrinology·1993

Related Experiment Video

Updated: Feb 14, 2026

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain
11:20

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain

Published on: May 7, 2018

12.7K

Aldosterone and potassium homeostasis

L Rabinowitz1

  • 1Department of Human Physiology, University of California, Davis, USA.

Kidney International
|June 1, 1996
PubMed
Summary

Plasma aldosterone and potassium levels do not fully explain potassium excretion after meals or daily rhythms. A novel kaliuretic reflex involving the central nervous system may regulate renal potassium excretion.

Area of Science:

  • Nephrology
  • Endocrinology
  • Physiology

Background:

  • Potassium homeostasis is crucial for cellular function.
  • Aldosterone and plasma potassium concentrations are traditionally considered key regulators of renal potassium excretion.
  • Existing models do not fully account for meal-induced or circadian variations in potassium excretion.

Purpose of the Study:

  • To investigate the regulators of renal potassium excretion, particularly in response to potassium-rich meals and during circadian rhythms.
  • To evaluate the roles of aldosterone and plasma potassium in these physiological processes.
  • To explore alternative regulatory mechanisms for potassium excretion.

Main Methods:

  • Review of existing evidence on aldosterone and plasma potassium effects on potassium excretion.

More Related Videos

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
08:34

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

15.8K
Monitoring Endoplasmic Reticulum Calcium Homeostasis Using a Gaussia Luciferase SERCaMP
08:41

Monitoring Endoplasmic Reticulum Calcium Homeostasis Using a Gaussia Luciferase SERCaMP

Published on: September 6, 2015

13.8K

Related Experiment Videos

Last Updated: Feb 14, 2026

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain
11:20

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain

Published on: May 7, 2018

12.7K
Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
08:34

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

15.8K
Monitoring Endoplasmic Reticulum Calcium Homeostasis Using a Gaussia Luciferase SERCaMP
08:41

Monitoring Endoplasmic Reticulum Calcium Homeostasis Using a Gaussia Luciferase SERCaMP

Published on: September 6, 2015

13.8K
  • Analysis of potassium excretion patterns in sheep following potassium-rich meals.
  • Examination of physiological circadian rhythms in renal potassium excretion.

    • Main Results:

    • Aldosterone exhibits kaliuretic activity primarily at supraphysiologic levels; its effect within the normal range is minimal.
    • Elevated plasma potassium significantly enhances kaliuresis, but only when above the normal range.
    • Meal-induced kaliuresis in sheep could not be attributed to changes in aldosterone or plasma potassium.
    • Circadian rhythms of renal potassium excretion occurred independently of aldosterone or plasma potassium fluctuations.

    Conclusions:

    • Current understanding of aldosterone and plasma potassium as sole regulators of potassium excretion is incomplete.
    • A kaliuretic reflex, potentially involving the central nervous system and other factors, is proposed to explain meal-induced and circadian potassium excretion.
    • Further research is needed to identify the specific factors involved in this putative reflex and their role in potassium homeostasis.