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[Changes in the level of lipid peroxidation in healthy pregnant women]
A cross-sectional study on the level of lipid peroxidation and nutrient intake of 44 healthy pregnant women (34-36 gestation week) at average age 24.9 +/- 4.5 years and 15 controls (nonpregnant, nonlactating) at average age 31.8 +/- 7.6 years, was carried out. The level of lipid peroxidation was measured by the concentration of TBA-reactive substance (TBARS) in plasma and red blood cells and the concentration of reduced glutathione in red blood cells. The nutrient intake was studied by 5-day diet record. The results obtained showed an activation of lipid peroxidation in pregnant women evidenced by a statistically significant increase of TBARS in red blood cells. Nutrient density of the protein of animal origin, vitamin C and zinc was significantly diminished in the diet of pregnant women but their average daily intake of protein and vitamin C was higher than the recommended dietary allowances. Obviously the activated lipid peroxidation during pregnancy could not be related to inadequate intake of nutrients with antioxidant activity but most probably is a result of hormonal changes.
A cross-sectional study on the level of lipid peroxidation and nutrient intake of 44 healthy pregnant women (34-36 gestation week) at average age 24.9 +/- 4.5 years and 15 controls (nonpregnant, nonlactating) at average age 31.8 +/- 7.6 years, was carried out. The level of lipid peroxidation was measured by the concentration of TBA-reactive substance (TBARS) in plasma and red blood cells and the concentration of reduced glutathione in red blood cells. The nutrient intake was studied by 5-day diet record. The results obtained showed an activation of lipid peroxidation in pregnant women evidenced by a statistically significant increase of TBARS in red blood cells. Nutrient density of the protein of animal origin, vitamin C and zinc was significantly diminished in the diet of pregnant women but their average daily intake of protein and vitamin C was higher than the recommended dietary allowances. Obviously the activated lipid peroxidation during pregnancy could not be related to inadequate intake of nutrients with antioxidant activity but most probably is a result of hormonal changes.