Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current techniques in mycobacterial detection and speciation

C D Herold1, R L Fitzgerald, D A Herold

  • 1Laboratory Service, VA Medical Center, San Diego, CA 92161, USA.

Critical Reviews in Clinical Laboratory Sciences
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomarkers of Recent Cannabis Use in Blood, Oral Fluid and Breath.

Journal of analytical toxicology·2021
Same author

Isotope dilution gas chromatography/mass spectrometry for platinum determination in urine.

Journal of the American Society for Mass Spectrometry·2013
Same author

Precision measurement of transition matrix elements via light shift cancellation.

Physical review letters·2013
Same author

[Inappropriate test methods in allergy].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2010
Same author

Safety of a SQ-standardised grass allergen tablet for sublingual immunotherapy: a randomized, placebo-controlled trial.

Allergy·2006
Same author

[Cross-reactive allergen clusters in pollen-associated food allergy].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2003
Same journal

Indirect methods for the verification of reference intervals in laboratory medicine.

Critical reviews in clinical laboratory sciences·2026
Same journal

Sustainability and waste reduction in clinical laboratories.

Critical reviews in clinical laboratory sciences·2026
Same journal

Aptamer-based biosensing strategies for influenza virus detection: a systematic and critical review of electrochemical and optical platforms.

Critical reviews in clinical laboratory sciences·2026
Same journal

Advancing patient safety through laboratory quality indicators in clinical pathology.

Critical reviews in clinical laboratory sciences·2026
Same journal

Blood biomarkers for the diagnosis of chorioamnionitis following preterm premature rupture of membranes: a systematic review and meta-analysis of studies since 2020.

Critical reviews in clinical laboratory sciences·2026
Same journal

Single cell mechanodeformation signatures as early biomarkers for hematological malignancies.

Critical reviews in clinical laboratory sciences·2026
See all related articles

Rapid identification of mycobacterial infections is crucial for controlling the tuberculosis resurgence. Newer diagnostic methods offer faster detection and speciation compared to traditional techniques.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Medical Diagnostics

Background:

  • Tuberculosis (TB) resurgence is linked to the increasing prevalence of Acquired Immunodeficiency Syndrome (AIDS).
  • Traditional biochemical methods for identifying and speciating mycobacterial infections are slow, requiring 4 to 8 weeks.
  • There is a critical need for rapid diagnostic methods to manage the growing TB epidemic.

Purpose of the Study:

  • To review and compare emerging methods for mycobacterial identification and speciation.
  • To assess the reliability, speed, and clinical utility of these newer diagnostic techniques.
  • To provide a synopsis of current literature on advanced TB diagnostics.

Main Methods:

  • Review of current literature on mycobacterial detection and speciation.

Related Experiment Videos

  • Analysis of newer methods including BACTEC, gene probes, nucleic acid amplification (NAA), ribosomal RNA amplification, high-performance liquid chromatography (HPLC), and gas chromatography-mass spectrometry (GC-MS).
  • Evaluation of diagnostic performance metrics such as reliability and time to result.

    • Main Results:

    • Newer methods significantly reduce the time required for mycobacterial identification and speciation, from weeks to days.
    • Techniques like NAA and molecular probes offer improved speed and potentially higher accuracy.
    • The clinical utility of these advanced methods is being established for effective TB management.

    Conclusions:

    • Rapid diagnostic methods are essential for combating the resurgence of tuberculosis.
    • Emerging technologies offer substantial improvements over classic biochemical techniques in speed and efficiency.
    • Further research and clinical integration of these advanced methods are vital for global TB control efforts.