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Related Experiment Videos

White coat hypertension

T G Pickering1

  • 1Hypertension Center, New York Hospital, Cornell University Medical Center, NY 10021, USA.

Current Opinion in Nephrology and Hypertension
|March 1, 1996
PubMed
Summary
This summary is machine-generated.

White coat hypertension, affecting over 20% of hypertensive patients, is a low-risk condition with minimal organ damage. Current treatment thresholds for white coat hypertension may need re-evaluation.

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Area of Science:

  • Cardiology
  • Hypertension Research

Background:

  • White coat hypertension (WCH) is prevalent, affecting 20% or more of the hypertensive population.
  • WCH is generally considered low-risk, lacking the organ damage and metabolic abnormalities of sustained hypertension.

Purpose of the Study:

  • To evaluate the current definition and treatment thresholds for white coat hypertension.
  • To assess the implications of using clinic blood pressure cutoffs versus ambulatory blood pressure monitoring.

Main Methods:

  • Review of recent studies on white coat hypertension prevalence and characteristics.
  • Analysis of the white coat effect (difference between clinic and ambulatory pressure) in hypertensive patients.
  • Examination of treatment outcomes for WCH, including effects on clinic and ambulatory pressures.

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Main Results:

  • The white coat effect is more pronounced in severe hypertension and does not correlate with target organ damage.
  • Drug treatment for WCH reduces clinic pressure more than ambulatory pressure, with the white coat effect persisting.
  • Current treatment thresholds based on WCH may be inappropriate.

Conclusions:

  • The prognostic outlook for patients with white coat hypertension appears benign.
  • Rethinking the definition and treatment thresholds for white coat hypertension is warranted.
  • Ambulatory blood pressure monitoring offers a more accurate assessment of hypertension.