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Updated: Aug 12, 2026
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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
Peripheral choroidal neovascularization
1W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, USA.
European Journal of Ophthalmology
|January 1, 1996
Summary
Peripheral choroidal neovascularization can present as subretinal lesions mimicking tumors. Diagnostic tools like fluorescein angiography and echography help differentiate these from choroidal metastasis.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Peripheral choroidal neovascularization (pCNV) can manifest as elevated subretinal lesions.
- These lesions may be misdiagnosed as choroidal tumors, including metastasis.
Purpose of the Study:
- To describe the clinical presentation of peripheral choroidal neovascularization.
- To evaluate diagnostic methods for differentiating pCNV from choroidal metastasis.
Main Methods:
- Retrospective review of 8 eyes with 11 peripheral subretinal lesions.
- Clinical examination, fluorescein angiography, and echography were utilized.
Main Results:
- Peripheral lesions were characterized by turbid subretinal fluid and exudate.
- The majority of patients were initially referred with a diagnosis of choroidal metastasis.
- Clinical examination with fluorescein angiography and echography effectively distinguished pCNV.
Conclusions:
- Peripheral choroidal neovascularization can present atypically without significant hemorrhage.
- Diagnostic imaging modalities are crucial for accurate differentiation from choroidal metastasis.
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