Chronic ectopic pregnancy after clinically successful methotrexate treatment of ectopic pregnancy

Persistent ectopic pregnancy, often a sequelae of conservative surgical procedures, is characterized by a residual trophoblastic activity site with rising or plateauing beta-human chorionic gonadotropin (hCG) titers after the initial treatment. Chronic ectopic pregnancy is a different entity which may be seen after expectant management of ectopic pregnancy and contains no active trophoblast with low or absent beta-hCG titers. A rare case with features of a chronic ectopic pregnancy, which followed successful methotrexate medical treatment of a persistent ectopic pregnancy, is presented.