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Characterization of the formation of interfacially photopolymerized thin hydrogels in contact with arterial tissue
M D Lyman1, D Melanson, A S Sawhney
1Focal Inc., Lexington, MA 02173, USA.
Biomaterials
|February 1, 1996
Abstract:
The aim of this study was to examine the conditions under which an interfacial photopolymerization process results in hydrogel barriers. Visible light initiated interfacial photopolymerization of a polyoxyethylene glycol (PEG)-co-poly(alpha-hydroxy acid) copolymer based on PEG 8000 macromonomer was performed on porcine aortic tissue, resulting in conformal hydrogel barriers. The process conditions were optimized in vitro for the formation of a 5-100 microns thick barrier.