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[Diagnosis of meconium aspiration syndrome by fluorometry technique]
Objective:
To establish a new diagnostic method of neonatal meconium aspiration syndrome (MAS).
Methods:
The fluorometry technique was used for examination of urine samples from three groups of neonates. The neonates were divided into 3 groups: Group I, MAS (n = 17); Group II, no MAS, but amniotic fluid with meconium stain (n = 24); Group III, normal control (n = 27). Urine fluorescence meconium index (UFMI) and urine meconium index (UMI) were calculated.
Results:
UFMI values of group I were higher than that of group II and III. The sensitivity and specificity of UFMI were 100% and 97% respectivety. However, it were 51% and 48% respectivety in UMI.
Conclusions:
UFMI is an index for identification of Zn-coproporphycin, and it is a more sensitive index for diagnosis of MAS.