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[Hepatitis C virus infection. Epidemiology]

A Bastie1, J M Pawlotsky, F Roudot-Thoraval

  • 1Service d'Hépatologie et de Gastroentérologie, Université Paris XII, CRETEIL, France.

Pathologie-Biologie
|October 1, 1995
PubMed
Summary

Hepatitis C virus (HCV) primarily spreads through blood, often via transfusions or drug use, with some cases having no clear cause. HCV infection is global, with varying prevalence and genotypes linked to specific transmission routes.

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[Not Available].

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2015

Area of Science:

  • Hepatology
  • Virology
  • Epidemiology

Background:

  • Hepatitis C virus (HCV) is a significant global health concern.
  • Transmission routes include parenteral (blood transfusion, intravenous drug use), sexual, intrafamilial, and mother-to-infant.
  • A notable percentage of cases lack identifiable risk factors.

Purpose of the Study:

  • To outline the primary and secondary transmission routes of Hepatitis C virus.
  • To identify populations at risk for HCV infection.
  • To describe the global prevalence and genotypic distribution of HCV.

Main Methods:

  • Review of existing literature on Hepatitis C virus transmission.
  • Analysis of epidemiological data on HCV prevalence worldwide.
  • Examination of studies on HCV genotypes and their geographical distribution.

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Main Results:

  • Parenteral transmission accounts for 60-70% of HCV cases, mainly through blood transfusions and intravenous drug use.
  • Other identified transmission routes include sexual, intrafamilial, and mother-to-infant.
  • HCV prevalence varies globally, from 0.5% in some European countries to over 5% in developing nations, with approximately 1% in France.
  • Genotype distribution differs geographically and is associated with specific contamination pathways.

Conclusions:

  • Hepatitis C virus has diverse transmission routes, with parenteral exposure being the most common.
  • Identifying at-risk populations and understanding global prevalence are crucial for control efforts.
  • Geographical variations in HCV genotypes correlate with transmission patterns, informing targeted public health strategies.