Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lymphatic function in the yellow nail syndrome

R H Bull1, D A Fenton, P S Mortimer

  • 1Department of Dermatology, St George's Hospital, London, U.K.

The British Journal of Dermatology
|February 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The utility of dynamic contrast-enhanced intranodal magnetic resonance lymphangiography (MRL) in the investigation of primary lymphatic anomalies.

Clinical radiology·2024
Same author

Clinical characteristics of male frontal fibrosing alopecia: a single-centre case series from London, UK.

The British journal of dermatology·2021
Same author

Cellulitis in chronic oedema.

The British journal of dermatology·2021
Same author

Frontal fibrosing alopecia: a descriptive cross-sectional study of 711 cases in female patients from the UK.

The British journal of dermatology·2020
Same author

Alopecia areata and frontal fibrosing alopecia: dimorphism by concurrence.

Clinical and experimental dermatology·2020
Same author

Detailed hair shaft analysis in a man with delayed-onset Chediak-Higashi syndrome.

The British journal of dermatology·2019
Same journal

Does loss of chromosome Y in blood contribute to the sex disparity of dermatitis and eczema at older ages?

The British journal of dermatology·2026
Same journal

Soluble CD83 reverses alopecia areata via IDO-mediated Treg cell activation.

The British journal of dermatology·2026
Same journal

Durability of Response to Icotrokinra in Adults With Moderate-to-Severe Plaque Psoriasis: One-Year Results From the Phase 3, Placebo- and Active Comparator-Controlled ICONIC-ADVANCE 1 & ICONIC-ADVANCE 2 Trials.

The British journal of dermatology·2026
Same journal

Clinicopathological features of lymphocytic thrombophilic arteritis and the relationship with livedoid vasculopathy - a case series of 36 patients.

The British journal of dermatology·2026
Same journal

Improving Prognostication for Cutaneous Squamous Cell Carcinoma.

The British journal of dermatology·2026
Same journal

Recurrent and novel GLTP variants in five patients with nonsyndromic epidermal differentiation disorder: phenotypic and genotypic expansion.

The British journal of dermatology·2026
See all related articles

Peripheral oedema in yellow nail syndrome (YNS) is linked to reduced lymphatic function, particularly in the legs and arms. This impairment appears functional and secondary, not the primary cause of YNS.

Area of Science:

  • Medicine
  • Lymphology
  • Dermatology

Background:

  • Peripheral oedema is a common clinical feature of yellow nail syndrome (YNS).
  • Previous studies using contrast lymphangiography suggested potential lymphatic abnormalities in YNS patients.

Purpose of the Study:

  • To quantitatively assess lymphatic function in the upper and lower limbs of patients with YNS.
  • To compare lymphatic function in YNS patients with normal controls and those with established lymphedema.

Main Methods:

  • Quantitative lymphoscintigraphy was employed to evaluate lymphatic drainage in 17 YNS patients, normal controls, and classical lymphedema patients.
  • Assessment included both upper and lower limbs.

Main Results:

Related Experiment Videos

  • Patients with YNS exhibited significantly reduced lymphatic drainage in their legs, though not to the extent seen in classical lymphedema.
  • Reduced lymphatic function was also observed in the arms of YNS patients.
  • Venous insufficiency was ruled out as a contributing factor to leg edema in YNS.

    • Conclusions:

    • The findings suggest that lymphatic abnormalities are not the primary underlying cause of yellow nail syndrome.
    • The observed lymphatic impairment in YNS appears to be secondary and predominantly functional, rather than structural.