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Perinatal limb ischemia: orthopaedic implications

J E Blank1, J P Dormans, R S Davidson

  • 1Department of Pediatric Orthopaedics, Children's Hospital of Philadelphia, Pennsylvania 19104-4399, USA.

Journal of Pediatric Orthopedics
|January 1, 1996
PubMed
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Perinatal limb ischemia often requires amputation in infants. However, many children treated for this condition achieve good function with prostheses, demonstrating positive long-term outcomes.

Area of Science:

  • Pediatric Surgery
  • Neonatal Medicine
  • Vascular Surgery

Background:

  • Perinatal limb ischemia is a serious condition affecting newborns.
  • It can lead to the need for amputation, impacting long-term function.
  • Understanding causes and outcomes is crucial for pediatric care.

Purpose of the Study:

  • To review the causes and treatment outcomes of perinatal limb ischemia requiring amputation.
  • To assess the functional results in patients treated for this condition.
  • To evaluate the efficacy of interventions and long-term prosthetic use.

Main Methods:

  • Retrospective review of 15 patients with perinatal limb ischemia requiring amputation.
  • Analysis of causes including arterial thrombosis, thromboembolism, and intravenous infiltrate.

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  • Evaluation of amputation timing, follow-up duration, and prosthetic use.
  • Main Results:

    • Common causes included arterial catheterization complications and hypercoagulable states.
    • Amputation was performed on average at 8.5 weeks postnatal age.
    • Of 11 followed patients, 9 achieved good function with prostheses.

    Conclusions:

    • Perinatal limb ischemia necessitating amputation can have varied causes.
    • Despite amputation, many children achieve good functional outcomes with prostheses.
    • Early intervention and prosthetic fitting are key to long-term rehabilitation.